9 results
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... • Hydralazine-Induced ... polyarteritis, drug-induced ... against MPO • Complement
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Methotrexate, Orlistat, Acyclovir ... Disease: Drug induced ... vasculitis, TMA ... differential #diagnosis #algorithm
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
The algorithm below ... : This algorithm ... The risk of acyclovir-induced ... short course of treatment ... provide empiric treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis ... IgG4+ cells" Treatment ... phenotypes #workup #treatment
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA Vasculitis ... Management Algorithm ... RTX over CYC, Reduced ... #Management #Treatment ... ACR2021 #Guidelines #algorithm
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
imprecise, and complemented ... and to adjust treatment ... #HIT #Heparin #Induced ... Thrombocytopenia #Algorithm
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
• Hematuria • Reduced ... tubulopathy) - Complement ... formation causing vasculitis ... microangiopathy Treatment