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diagnosis management rheumatology differential infectiousdiseases vasculitis champs chlamydia classification disease hematology huv igg4 leishmaniasis low mnemonic pathophysiology phenotypes psittaci psittacosis
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
with response to treatment ... rheumatoid factor), ± hypocomplementemia ... IgG4+ cells" Treatment ... phenotypes #workup #treatment
Psittacosis Pathogen: Chlamydia psittaci - obligate intracellular gram negative Transmission: • Birds are the primary reservoir •
bird contact • Complement ... danger of aerosol) Treatment ... first line of treatment ... Chlamydia #psittaci #microbiology ... diagnosis #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
Neutralization of complement ... culture, PCR, K39) Treatment ... diagnosis #management #treatment ... infectiousdiseases #microbiology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... Adenocarcinoma Treatment
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