48 results
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
— Normal Bile Ducts ... Infiltrative • Cirrhosis ... • Common Bile Duct ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
Platelets in Cirrhosis ... Bleeding in Cirrhosis ... ) Budd Chiari Syndrome ... Circulation #Disorders #Hepatology ... #Gastroenterology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
(eg, hemolytic anemias ... drugs, biliary cirrhosis ... carcinoma of biliary duct ... pressure on bile duct ... #differential #causes
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
• Gilbert's Syndrome ... Crigler-Najjar Syndromes ... - Usually has Duct ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 • Congestive heart failure
 • Constrictive
Causes of Pleural ... - Oncotic • Cirrhosis ... • Asbestos • Uremia ... Diagnosis #Algorithm #Hepatology ... #causes
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... Primary biliary cirrhosis ... disease (Budd-Chiari syndrome ... #Differential #Hepatology ... #Cirrhosis #Causes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... causes cholestasis ... → Cirrhosis/Liver ... Primary #Biliary #Cirrhosis ... diagnosis #workup #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... or secondary to cirrhosis ... 3) Sinusoidal: Cirrhosis ... post-sinusoidal: Budd-Chiari syndrome ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Clues to non-cirrhotic ... Post-Hepatic: • Cardiac causes ... • Budd Chiari syndrome ... #hepatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... Diagnosis #Algorithm #Causes ... #Hematology