14 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... food binges, etc Hyperglycemia ... #dka #hhs #pathophysiology ... #comparison #endocrinology ... #diabetes #diabetic
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... pathways that lead to hyperglycemia ... #Pathophysiology ... Targets #Drug #Endocrinology
Stages in the Development of Diabetes Type 1

#Diabetes #Type1 #TypeI #DM1 #Stages #Development #Pathophysiology #Timeline #Diagnosis
Development of Diabetes ... Type 1 #Diabetes ... #Type1 #TypeI #DM1 ... #Development #Pathophysiology ... Timeline #Diagnosis #Endocrinology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... depletion and hyperglycemia ... abnormalities, including hyperglycemia ... #Pathophysiology ... #Endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
: Weight gain, Hypoglycemia ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Does not cause hypoglycemia ... mL/minute/1.73 rm2 ... mL/minute/1.73 m2 ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
Assessment of diabetic control:
 - Any episodes of hypoglycaemia, diabetic ketoacidosis, hospital admission? 
 - Is
Assessment of diabetic ... Any episodes of hypoglycaemia ... still awareness of hypoglycaemia ... #primarycare #DM1 ... #Peds #Pediatrics
The “twin cycles” of diabetes, first introduced by Roy Taylor in 2008.  
#fatty liver #fatty
twin cycles” of diabetes ... fatty pancreas #diabetes ... #t2d #dm2 #insulin ... resistance #pathophysiology ... #endocrinology
Understanding the pathophysiology of hyperglycemia

#DKA #Diabetic #Ketoacidosis #Endocrinology #Pathophysiology
Understanding the pathophysiology ... of hyperglycemia ... #DKA #Diabetic ... #Ketoacidosis #Endocrinology ... #Pathophysiology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... a low risk of hypoglycemia ... Pharmacology #Dosing #Diabetes ... #DM2 #Endocrinology