20 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... food binges, etc Hyperglycemia ... #dka #hhs #pathophysiology ... #comparison #endocrinology ... #diabetes #diabetic
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
- Pharmacology Summary ... : Weight gain, Hypoglycemia ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... pathways that lead to hyperglycemia ... #Pathophysiology ... Targets #Drug #Endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology Summary ... Does not cause hypoglycemia ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Stages in the Development of Diabetes Type 1

#Diabetes #Type1 #TypeI #DM1 #Stages #Development #Pathophysiology #Timeline #Diagnosis
Development of Diabetes ... Type 1 #Diabetes ... #Type1 #TypeI #DM1 ... #Development #Pathophysiology ... Timeline #Diagnosis #Endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... EricsMedicalLectures/featured #diabetes ... comparison #management #endocrinology ... #dm2
Summary and links to five landmark trials of intensive control vs standard therapy in DM2:

 UKPDS
Summary and links ... standard therapy in DM2 ... VisualAbstract #Endocrinology ... #PrimaryCare #Diabetes ... #DM2 #Type2 #Landmark
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... depletion and hyperglycemia ... abnormalities, including hyperglycemia ... #Pathophysiology ... #Endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology Summary ... • Euglycemic diabetic ... #Pharmacology #Summary ... #DM2 #diabetes ... #endocrinology
Assessment of diabetic control:
 - Any episodes of hypoglycaemia, diabetic ketoacidosis, hospital admission? 
 - Is
Assessment of diabetic ... Any episodes of hypoglycaemia ... still awareness of hypoglycaemia ... #primarycare #DM1 ... #Peds #Pediatrics