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Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell Crises ... Clinical Manifestations ... Diagnosis #Management #Hematology ... Manifestations #Workup
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... neutrophils #AML #Clinical ... #Hematology #Pathology
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
In this case, the ... Leukoerythroblastosis #Hematology ... #Pathology #Smear ... #Microscopy #Clinical
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
features in most cases ... leukemia #APL #APML #Pathology ... #Hematology #Clinical
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... ) - Clinical symptoms ... Diagnosis #Signs #Hematology ... #Workup
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Hodgkin Lymphoma - Clinical ... Lymphoma (90-95% of cases ... Hodgkin Lymphoma Workup ... classification #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Hypercoagulable Workup ... - 1 or more clinical ... maternal chromosomal causes ... Hypercoagulable #Workup ... Algorithm #diagnosis #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma) Clinical ... IFE, FLC assay Pathology ... Oncology #Diagnosis #Workup ... #Hematology