23 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... Potassium #Binding #Hyperkalemia
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization; changes ... repolarization causes ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... cantaloupe #hyperkalemia
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... Metabolic acidosis - Hyperkalemia ... images/12834 #hyperkalemia
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
treatments) occur in high ... 6L/day) • For hyperkalemia ... with Ca only if EKG ... changes, otherwise ... treat with "hyperkalemia
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... potassium and ECG ... changes • 5.5 ... , asystole #hyperkalemia ... #potassium #high
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... only if no clear cause ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... • Low EABV (e.g ... • Obstruction High ... • NSAlDs #Hyperkalemia ... Diagnosis #Algorithm #Causes
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC count cause ... tinnitus, visual changes ... WBC >100k, + lab signs ... hydration - Hyperkalemia ... unless worrisome EKG
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... disorders including hypokalemia ... renal bruit or signs ... hormonal excess or hypokalaemia ... Hyperthyroidism, Hypercalcemia