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diagnosis nephrology syndrome treatment causes differential rhabdomyolysis gitelman hematology k leukostasis lysis oncology summary tumor tumorlysis
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
8.0 mg/dL • Potassium ... : • Hypovolemia ... hydroxide • Hyperkalemia ... treatment • Hypocalcemia ... #diagnosis #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Acidosis, Cell Lysis (TLS ... emcrit.org/ibcc/hyperkalemia ... of hyperkalemia ... #Hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... HIV, Influenza, TSS ... • LDH ↑ • Hyperkalemia ... Monitor potassium ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... HIV, Influenza, TSS ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium ... Dialysis for severe hyperkalemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... hydration - Hyperkalemia ... Lysis #Syndrome #TLS ... #diagnosis #management
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... #pathophysiology ... #Hypokalemia
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