9 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Hyperuricemia • Hyponatremia ... Monitor potassium ... per day until stable ... #treatment #nephrology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... intracellular calcium causes ... (or low potassium ... Pathophysiology #cardiology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
aldosterone which does a lot ... sodium, which causes ... this pathway, ending ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... differential #diagnosis #table ... #sodium #nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Loss of sodium/Potassium ... heat illness → Hypernatremia ... Liver injury, Rhabdomyolysis ... - Hyperkalemia ... differential #diagnosis #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
only if no clear cause ... Elimination (see Table ... Treatments: • K-Binding ... Management #Treatment #potassium ... #nephrology #K
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
patient causing hypovolemia ... the determined cause ... algorithm #management #cardiology ... #treatment #table ... icu #clinical #pharmacology