7 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... rapidly develops (DIC ... infiltration) Differential ... #Pregnancy #hepatology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... <45% and SF is normal ... with elevated HIC ... algorithm #diagnosis #management ... #hepatology #gastroenterology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... heat illness → Hypernatremia ... Collapse: • Pathophysiology ... - Core temp normal ... cardiomyopathy, ARDS, DIC
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... APML #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... thrombocytopenia • Liver ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Excessive activation ... Sjogren's • CSF: - Abnormal ... Transverse Myelitis Treatment ... #neurology #differential