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diagnosis hematology bruising oncology classification cvid dic disseminated hemostasis hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular lfts liverenzymes lymphoma mds myelodysplasia myelodysplastic
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Thrombocytopenia ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
- Normal coagulation ... DIC • Severe Liver ... Disease: - Impaired ... #treatment #management ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... Bile Ducts • Common ... • Pancreatic cancer ... #Causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... intravascular coagulation ... defects in the common ... discern these causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... Lymphoma or other cancers ... gastric and breast cancer ... specifically immune thrombocytopenia ... DDX - Other causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... by bleeding (petechiae ... Most common cytopenia ... Myeloproliferative Disease ... blood count with differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
(NSHL) - (most common ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #oncology #management
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