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diagnosis hematology bleeding bruising oncology classification cvid dic disseminated hemostasis hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular lfts liverenzymes lymphoma mds myelodysplasia
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Thrombocytopenia ... Destruction • Abnormal ... Iatrogenic) • Liver ... #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Cholestatic disease ... Bile Ducts • Common ... • Pancreatic cancer ... #Causes
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
- Normal coagulation ... DIC • Severe Liver ... Disease: - Impaired ... #treatment #management ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... • Liver diseases ... Lymphoma or other cancers ... specifically immune thrombocytopenia ... DDX - Other causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... inhibitor of a coagulation ... Xa inhibitors (variable ... defects in the common ... discern these causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... MDS carries a variable ... Most common cytopenia ... Myeloproliferative Disease ... blood count with differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
(NSHL) - (most common ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #oncology #management
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