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dermatology rheumatology algorithm classification agglutinin anemia cold cryofibrinogenemia cryoglobulinemia disease hemolytic hypopigmentation mds monoclonal myelodysplasia myelodysplastic nonpalpable palpable paraproteinemias petechiae
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Tanning • Adverse cutaneous ... McCune Albright syndrome ... #disorders #skin ... #dermatology #Differential ... #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cause Organ Damage ... Type III Often Secondary ... Henoch-Schönlein purpura) • Cutaneous
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... leakage of RBC's secondary ... #Diagnosis #hematology
Skin Hyperpigmentation - Differential Diagnosis Algorithm Diffuse: • Tanning • Adverse cutaneous drug eruption • Addison's disease
Skin Hyperpigmentation ... Tanning • Adverse cutaneous ... #disorders #skin ... #dermatology #Differential ... #causes
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... cryoglobulinemia Associated Disorders ... • Negative causes ... Antiphospholipid syndrome ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... strong sign of cutaneous ... Serologies for Cryoglobulins ... differential #diagnosis ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
in primary or secondary ... - Collagen disorders ... immunoglobulins & cryoglobulins ... • Skin biopsy ... #Causes #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... hypertrichosis, hyperpigmentation ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Agglutinin Syndrome ... presentation) • Cutaneous ... younger pts) Differential ... hemolytic #anemia #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Most common extra cutaneous ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
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