12 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... thigh bones -> chronic ... Wilson's disease • hypothyroidism ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... - Differential ... Endocrine • Hypo/Hyperthyroidism ... Pulmonary Disease Neurologic ... Myasthenia Gravis Pharmacologic
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Thyrotoxicosis - Wet Beriberi ... disorders - Chronic ... PP and systolic hypertension ... #Diagnosis #Pathophysiology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Diagnosis Algorithm ... Hypertensive: ... • High Al, Low R ... Al, Low R - Pseudo-hyperaldosteronism ... #nephrology #causes
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Diagnosis Framework ... Manifestations Causes ... Lactation - Hyperthyroidism ... #beriberi #nutrition ... #pathophysiology
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Diagnosis: ... • ↓ Low TSH • ... psychosis - CHF - Hypotension ... #causes #diagnosis ... #differential #
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Diagnosis Algorithm ... CHF, cirrhosis, hypotension ... Creatinine • Chronic ... #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Endocrine: Hypo/Hyperthyroidism ... injured muscles - HYPOTENSION ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Normal/low ... Hypomagnesemia • Hypertension ... the indicated causes ... #differential # ... diagnosis
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Nephrotic Syndrome, Chronic ... Renal Failure, Hypothyroidism ... #Algorithm #diagnosis ... #causes #nephrology ... #sodium #low