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Class I Antiarrhythmics and their Key Pharmacologic Properties Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer") Class IB
Class I Antiarrhythmics ... Properties Class ... IC = Flecainide ... channel blockade: IC ... the ERP: IA > IC
Antiarrhythmics - Vaughan Williams Classification Class I (Ia, Ib, Ic) - Na+ Channel Blockade • Slows depolarization
Classification Class ... I (Ia, Ib, Ic) ... Widens QRS complex Class ... prolongs PR interval Class ... Classification #Classes
Torsades de Pointes •Precipitated by drugs that prolong the QT interval •Class IA antidysrhythmics (procainamide, quinidine)
QT interval •Class ... quinidine) •Class ... IC antidysrhythmics
Antiarrhythmic Drug Classes IA: "Police Department Questions IB: Liquored Man IC: For Peeing, Ill: After Drinking
Antiarrhythmic Drug Classes ... Liquored Man IC ... Lidocaine Mexiletine IC ... Antiarrhythmic #Drug #Classes
Antiarrhythmics - Sodium Channel Blockers Subclasses, Mechanisms, Indications, Side Effects la - Quinidine, Procainamide lb - Lidocaine, Mexiletine Ic -
Lidocaine, Mexiletine Ic ... Channel #Blockers #ClassI
Antiarrhythmic Medications - Vaughan-Williams Classification • Class I (Ia, Ib, Ic) • Class II • Class
Classification • Class ... I (Ia, Ib, Ic) ... • Class II • ... Class III • Class
Antiarrhythmic Medications - Vaughan-Williams Classification • Class I (Ia, Ib, Ic) • Class II • Class
Classification • Class ... I (Ia, Ib, Ic) ... • Class II • ... Class III • Class
Torsades de Pointes • "Twisting of the pointes" • QRS axis swings from positive to negative direction
interval Class ... quridine) Class ... IC antidysrhythmics
Common sodium channel blockers which cause QRS widening. Anticonvulsants: - Carbamazepine Antidysrhythmics: - Group
- Group IA and IC ... Differential #Drugs #Classes
Antiarrhythmic Drugs CLASS IA • Procainamide, Quinidine, Disopyramide CLASS 1B • Lidocaine, Mexiletine CLASS 2 • Propranolol, Esmolol CLASS 4
Antiarrhythmic Drugs CLASS ... Disopyramide CLASS ... Lidocaine, Mexiletine CLASS ... Propranolol, Esmolol CLASS ... #Medications #Classes
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