42 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
to Kidney: Anti-GBM ... With associated pulmonary ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
A summary of GI Lymphomas - Primary Lymphoid Neoplasms of the GI Tract
T-Cell
 - EATL
 -
GIT B-Cell - EBV ... Laura Brown @lauraebrown ... Lymphomas #GITract #hematology ... hemepath #pathology #differential ... #diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... antibody, Anti-GBM ... usually low in anti-GBM ... Renal #Syndromes #differential ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... #management #treatment ... #summary #rheumatology
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
and COPD The diagnosis ... summary of the differential ... asthma-COPD overlap; ICS ... corticosteroids; LABA ... #Diagnosis #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... organ dysfuxtion, ICU ... #management #hematology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... Pulmonary arterial ... receptor type II-like ... Classification #Diagnosis ... #Differential #
RADIAL HEAD FRACTURE 
Radial head fractures are the most common elbow fracture in adults and are
Tenderness to lateral ... fracture • ED Management ... MH/CCF/CWRU EM ... Radiology #XRay #Diagnosis ... #Management #Orthopedics
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... immobility • Critical ... Illness Myopathy (ICU ... #Elevated #CK #differential ... #diagnosis #rhabdomyolysis