11 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
5 or elevated Cr ... common • Imaging: CXR ... - pulmonary opacities ... organ dysfuxtion, ICU ... #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
rest LTBI (-) Immune ... characteristic features Clinical ... and Culture • CXR ... disease • Check CXR ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
rest LTBI (-) Immune ... characteristic features Clinical ... and Culture • CXR ... disease • Check CXR ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... accumulation of clinical ... Purtilo (XLP) Acquired ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... leukoencephalopathy (PML ... Leishmaniasis Differential ... #Diagnosis #Management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... Blood cultures • CXR ... westermani • Other: TB ... Lung #Abscess #pulmonary ... #differential #
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
transplantation CLINICAL ... and cauda equina TREATMENT ... intensive care unit (ICU ... ventilation is required ... Syndrome #diagnosis #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... is generally required ... until immune recovery
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... Diagnosis and Management ... aeruginosa Clinical ... Yield of blood CX ... #treatment #Pulmonary
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... & Dry) is the treatment ... #diagnosis #differential ... #algorithm #management ... #criticalcare #icu