10 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
5 or elevated Cr ... - pulmonary opacities ... initiation • Differential ... organ dysfuxtion, ICU ... #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
rest LTBI (-) Immune ... characteristic features Clinical ... and Culture • CXR ... disease • Check CXR ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
rest LTBI (-) Immune ... characteristic features Clinical ... and Culture • CXR ... disease • Check CXR ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... Purtilo (XLP) Acquired ... Drugs, Unknown cause ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess - Clinical ... westermani • Other: TB ... Lung #Abscess #pulmonary ... causes #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... leukoencephalopathy (PML ... Leishmaniasis Differential ... #Diagnosis #Management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... and cauda equina TREATMENT ... intensive care unit (ICU ... Syndrome #diagnosis #management
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... should be based on clinical ... Antimicrobial treatment ... is generally required ... until immune recovery
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... the determined cause ... #diagnosis #differential ... #algorithm #management ... #criticalcare #icu
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... cardiomyopathy • Pulmonary ... Avoid ARBs • ICD ... #cardiology #treatment