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management druginduced erythematosus systemic comparison differential leukemia manifestations mucocutaneous oncology polychondritis relapsing signs summary table tafro thrombocytopenia vasculitides vasculitis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... SCLE-DIL (terbinafine ... Discontinuation of causal ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... versus DIL • ... life-threatening • Treatment ... Management #Summary #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation on skin ... #diagnosis #signs ... #symptoms #complications
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Disease Classification ... : • Symptoms limited ... #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
NPSLE rare, Malar rash ... SCLE-DIL (terbinafine ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... vasculitis, and SLE ... #rheumatology # ... classification
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Fibrinolysis & DIC ... CLL -> Invade Skin ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... and the systemic symptoms ... Hypoalbuminemia Treatment ... #management #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
• Inner ear • Skin ... such as: • SLE ... Multiple myeloma Complications ... affected tissue Treatment ... Polychondritis #rheumatology
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