26 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... Life-threatening ... : high fever, CRP ... #AOSD #rheumatology ... #diagnosis #management
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
or absence of fever ... If fever is present ... includes Kawasaki disease ... , scarlet fever, ... #Diagnosis #Dermatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... bartonella (oroya fever ... #Algorithm #workup ... #hematology #testing
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... erythematosus [SLE], AOSD ... #Management #Hematology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
correlates with time of fever ... Daily high spiking fever ... - Fever spikes ... Fever of at least ... #AOSD #diagnosis
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... should be TS and SF level ... disease. ... and hematologic ... #diagnosis #management
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... dependent injury (ie ... disease 6-9 mo ... #algorithm #gastroenterology ... #hepatology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
in vasculitic diseases ... petechiae/purpura with fever ... disseminated gonococcal disease ... petechiae/purpura with fever ... #Diagnosis #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... • Autoimmune diseases ... Adult-onset Still disease ... #management #treatment
Algorithm for the Evaluation of Acute Diarrhea (< 7 days)
Are the following present?
   1.
Algorithm for the ... Bloody diarrhea, fever ... Acute #Diarrhea #management ... #algorithm #workup ... #diagnosis