25 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... dependent injury (ie ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... HEV, EBV, CMV), Alcohol-related ... biopsy if: • ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... • Iatrogenic: DILI ... ALT Ratios: • Alcoholic ... #algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure Infections Alcohol-Associated ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... HSV • Toxic: Alcohol ... Hepatic Artery: Shock ... Causes #Acute #algorithm ... #hepatology
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... use ABx coverage if ... can be bridge to Liver ... #hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
for admission (if ... different) PMHx: - Focus ... GTT, indirect bili ... of hypotension, shock ... Calling #Referral #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
ALT Ratios: • Alcoholic ... Unconjugated Bili ... > 90% of Total Bili ... #chemistry #diagnosis ... #differential #Hepatology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Diagnosis Framework ... Insufficiency, Liver ... #criticalcare # ... algorithm #treatment ... #management
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... If fever is present ... , and toxic shock ... to scombroid or alcohol ... Erythematous #Rash #Algorithm