10 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
IFN-γ-activated ... TB: • Fever • ... Tuberculosis Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
absent NK cell activity ... • Bicytopenia Treatment ... If no response HLH ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Hepatitis (eg Viral) Management ... regarding need for treatment ... azathioprine (check TPMT activity ... AIH #Diagnosis #Management ... #Hepatology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
IFN-γ-activated ... TB: • Fever • ... Tuberculosis Treatment ... TB #Diagnosis #Management ... #Treatment #ActiveTB
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
cirrhosis • Intra-pulmonary ... perfusion scanning or pulmonary ... ) on room air Treatment ... supplemental oxygen if ... #treatment #hepatology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
Transthoracic echocardiogram ... pressure < 15mmHg TREATMENT ... hemodynamics Liver ... Hypertension #diagnosis #management ... #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... APML #diagnosis #management ... #hematology #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
decrease in HIV-1 RNA level ... Lymphadenitis, pulmonary ... • Persistently active ... continued • If ... Differential #Diagnosis #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... • PET scan - activity ... marrow biopsy - if ... Hodgkin Lymphoma Treatment ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... search for and treatment ... absent NK-cell activity ... Treatment Approach ... #Hematology #HemeOnc