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treatment hepatology rheumatology algorithm differential hemophagocytic lymphohistiocytosis summary aosd arthritis blood classification gastroenterology hepatitis injury kawasaki liver product reactions stills
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... age, however the disease ... If no response HLH ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, ↓ Fibrinogen level ... • Autoimmune diseases ... Adult-onset Still disease ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... ALT ↑ bilirubin level ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
regarding the diagnosis ... should be TS and SF level ... disease. ... and hematologic ... #management #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Onset: Usually in infancy ... ▪ Autoimmune diseases ... Approach • Initial management ... #Management #Hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... (KD) - Diagnosis ... and Management ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
If these factors ... syndrome (SSS) in infants ... If fever is present ... includes Kawasaki disease ... #Diagnosis #Dermatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Venoocclusive disease ... PBC, PSC, IgG4, HLH ... #differential #diagnosis ... #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... dependent injury (ie ... disease 6-9 mo ... #differential #Diagnosis ... gastroenterology #hepatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... Life-threatening ... AdultOnset #Stills #Disease ... #AOSD #rheumatology ... #diagnosis #management
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