47 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... Life-threatening ... synovitis (40%) Treatment ... #diagnosis #management ... #treatment
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... “low risk” an infant ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... Peds #Febrile #Infant
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Treatment - Mild ... : NSAIDS Treatment ... • If uncontrolled ... #AOSD #diagnosis ... #rheumatology #management
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Kawasaki Disease ... (KD) - Diagnosis ... #rheumatology #pediatrics ... #diagnossi #management ... #treatment
Bronchiolitis
Bronchiolitis is a viral inflamation of the bronchioles and the commonest LRTI in under 1s'. It's
REMEMBER - infants ... (particularly if ... Bronchiolitis #pediatrics ... #diagnosis #management ... #peds #treatment
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... Insufficiency, Liver ... , Severe Valve Disease ... #criticalcare # ... #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... age, however the disease ... • Bicytopenia Treatment ... If no response HLH ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... 50% in nec fasc Diagnostic ... (2+): kidneys, liver ... necrosis STSS Treatment ... #management #diagnosis