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hematology treatment checklist hemophagocytic lymphohistiocytosis workup arthritis blood hodgkins icu lymphoma product reactions summary syndrome acromegaly activation admissions admitting agitation
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... , ↓ Fibrinogen level ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... If no response HLH ... #management #treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... Clinical Presentation ... Approach • Initial management ... #Management #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • Dyspnea • Fever ... lymph node biopsy (diagnostic ... marrow biopsy - if ... #oncology #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... but might occur if ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (to support a diagnosis ... clinical features ... laboratory #workup #diagnosis ... #testing #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Prophylaxis: • Attempt if ... high risk if WBC ... Subacute-Acute: • Common: fever ... #management #hematology ... #oncology
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
• Persistent fever ... • Aggressive management ... Internet Book of Critical ... Endocarditis #checklist #criticalcare ... #diagnosis #management
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... Summary Clinical ... active ROM +/- fever ... 90% sensitive in pediatrics ... anal Cxs) • *** If
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