13 results
hematology treatment hemophagocytic hlh lymphohistiocytosis product reactions syndrome anemia anesthesia anesthesiology aplastic apml chagas checklist classification coagulation dic differential differentiation
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... acute or subacute febrile ... If no response HLH ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
in Anaesthesia If ... devices, especially infants ... • Intracranial blood ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
high risk if WBC ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... #management #hematology ... #oncology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Mediated: • Febrile ... Causes purpura & ... TRALI): Leading cause ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Mediated: - Febrile ... Causes purpura & ... TRALI): Leading cause ... #Transfusions #diagnosis ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... febrile, give abx ... Syndrome #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... index < 2 • EPO Level ... result from low blood ... #hematology #diagnosis ... #management
Newborn Infant - Routine Examination Birthweight, gestational age and birthweight percentile are noted. General observation Of the baby's
Newborn Infant - ... When the diagnosis ... measuring the blood ... Examination #Peds #Pediatrics ... #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... dL) - Heparin if ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
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