20 results
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... #Febrile #Infant
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... a primary hematologic ... When do you do a BM ... #Differential #Diagnosis ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... acute or subacute febrile ... If no response HLH ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... and Management ... , Cough • +/-Nausea ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... extremities during febrile ... • If uncontrolled ... #rheumatology # ... management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
many differential diagnoses ... ANA) [especially if ... 9) Unexplained fever ... including in children (pediatric ... erythematosus #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... febrile, give abx ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Prophylaxis: • Attempt if ... high risk if WBC ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... index < 2 • EPO Level ... Anemia #oncology #hematology ... #diagnosis #management