7 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Infants #Diagnosis ... #Management #Pediatrics ... #Algorithm #LP ... #Antibiotics #Risk ... Stratification #Fever
“Step by Step” – the new kid on the block – aims to risk stratify this
” an infant with ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #Algorithm #LP
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... #EBM #Management ... #Pediatrics #Peds ... #Febrile #Infant ... StepByStep #Algorithm #LP
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... frequently affects infants ... acute or subacute febrile ... #management #treatment ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... high risk if WBC ... Rare: DAH, acute febrile ... Differentiation #Syndrome ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... Treatment: - If ... febrile, give abx ... #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... consideration in febrile ... hyperinflammatory syndrome ... Onset: Usually in infancy ... #Management #Hematology