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hematology treatment blood differential disease hemophagocytic hlh lymphohistiocytosis peds product reactions syndrome anemia anesthesia anesthesiology aplastic apml assessment atopic bleeding
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... and Management ... , Cough • +/-Nausea ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... following: • Fever ... If no response HLH ... #management #treatment ... #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
in Anaesthesia If ... Actively maintained fever ... devices, especially infants ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
many differential diagnoses ... ANA) [especially if ... 9) Unexplained fever ... including in children (pediatric ... erythematosus #rheumatology
Assessment of the Child with Eczema Distribution of atopic eczema - The distribution of eczema tends to
In infants, the ... interfere with life ... condition and its management ... primarycare #peds #pediatrics ... #diagnosis #atopic
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Prophylaxis: • Attempt if ... high risk if WBC ... Subacute-Acute: • Common: fever ... #management #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
either abnormal intact ... (rarely IgD or IgE ... ) • Increased level ... #Significance #hematology ... #diagnosis #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... index < 2 • EPO Level ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... • Factor VIII level ... discern these causes ... #Differential #Diagnosis ... #Hematology
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