28 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... fraction < 20% Differential ... #management #treatment ... #rheumatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
The Liver Consult ... for admission (if ... on prior Liver/ ... disease work up ... - Liver US
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
diagnosis and treatment ... μg/L, liver biopsy ... disease. ... and hematologic ... algorithm #diagnosis #management
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... Life-threatening ... #Disease #AOSD ... #management #treatment
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... disease), HBsAg ... #hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced Liver ... or symptoms of liver ... disease 6-9 mo ... Drug #induced #Liver ... Idiosyncratic #differential
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... /splenomegaly, liver ... Treatment - Mild ... • If uncontrolled ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... thrombocytopenia • Liver ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
active ROM +/- fever ... , chills, malaise ... necrosis, Lyme disease ... viral arthritis Workup ... 90% sensitive in pediatrics
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, ↓ Fibrinogen level ... +, Adult-onset Still ... disease, Infection ... Lymphohistiocytosis #diagnosis #management ... #rheumatology