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diagnosis rheumatology treatment algorithm lupus classification erythematosus summary acidosis anemia approach arthritis cardiology ckd clues comparison disorders druginduced elevation endocarditis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... disease, decrease ... test, ANA (e.g., SLE ... disease), HBsAg ... #Workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... • Immunologic Workup ... Positive in 60-80% of cases ... : Chronic disease ... #Summary #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... ): SS, SC, SE, Sβ ... RBC inclusions - If ... Diagnosis #Algorithm #workup ... #hematology #testing
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... : Chronic disease ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, ↓ Fibrinogen level ... : SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Better call hematology ... some time, let’s see ... As with many disease ... #hematology
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... ANA) [especially if ... 9) Unexplained fever ... including in children (pediatric ... SLE) 10) When
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... approach to the differential ... disease) and augmentation ... Diagnosis #Treatment #management ... #nephrology #sodium
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
acute rheumatic fever ... ), RA, crystal disease ... Chronic = RA, SLE ... #approach #workup ... #differential #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... Summary Causes ... of underlying disease ... #nephrology
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