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diagnosis differential causes nephrology hematology algorithm management reactions allergy hypersensitivity pharmacology vasculitis cardiology rheumatology table clinical glomerulonephritis shock antiarrhythmic blood
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia Classification ... Types Type 1 ... Mixed: • Type ... • Type 3 (25% ... Cryoglobulinemia #Classification
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Transferrin • Gamma: IgM ... , IgG, IgA, RF, ... Subtypes #algorithm #classification ... #Types #hematology
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
Types of hypersensitivity ... reactions Type ... (Anaphylaxis) Type ... II - IgG or IgM ... #Classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... Their Mechanisms Type ... II - IgG or IgM ... Type Ill - IgG and ... #Classification
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Immunological Mediator: IgM ... + IgG • Immunological ... #Classification
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm • GI disorders: Celiac disease, Crohn's disease,
Causes of Secondary ... IgA Nephropathy ... Schistosomiasis • Cancers: IgA ... #Secondary #IgA ... #Nephropathy #Causes
Comprehensive pathogenesis of IgA Nephropathy (i.e Berger’s Disease). IgA Nephropathy is the most common cause of
pathogenesis of IgA ... IgA Nephropathy ... - What type of Hypersensitivity ... is IgA Nephropathy ... complement to IgA
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Normal C3/C4 (IgA ... ): IgA Nephropathy ... diagnosis #nephrology #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulins are Igs ... Types: • Type ... or polyclonal IgM ... • IgA vasculitis ... #classification
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
maternal chromosomal causes ... and IgM • Beta ... Antibodies, IgG ... Cardiolipin Antibody, IgA ... Glycoprotein 1 Antibody, IgA
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