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management oncology rheumatology activation anemia aplastic apml atopic clinical dermatitis differentiation dress eczema hemophagocytic hlh leukemia leukostasis lymphohistiocytosis lysis macrophage
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... + lab signs of end ... #TLS #diagnosis ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... disease: symptomatic treatment ... Hospital of Baltimore IM ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... to repair DNA, as ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... coagulopathy, RRT/IMV as ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... It presents as an ... following: • Fever ... • Bicytopenia Treatment ... #hematology
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
#diagnosis #causes ... #atopy #atopic ... dermatitis #eczema #dermatology ... corticosteroids in dermatology ... EL, Richardson IM
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... and lower jaw Treatment ... diagnosis #management ... #Dermatology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
) ▪ Malaise, fever ... syphilis may appear as ... resembling rashes caused ... Syphilis #Rash #Diagnosis ... Clinical #Photo #Dermatology
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