18 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... of Sickle Cell Crises ... Clinical Manifestations ... Diagnosis #Management #Hematology ... Workup #Algorithm #Ddxof
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... life-threatening • Treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... of SLE versus DIL ... Positive in 60-80% of cases ... life-threatening • Treatment
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... resembling rashes caused ... #Diagnosis #Clinical ... #Photo #Dermatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... disease: symptomatic treatment ... Hospital of Baltimore IM ... DRESS #Syndrome #dermatology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... inflammation persist → DIC ... possible Patient's clinical ... #dermatology #clinical
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Discontinuation of causal ... • Evolution: ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology