18 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... smoking, etoh, decr activity ... #Osteoporosis #pathophysiology ... #signs #symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... ß-glucocerebrosidase activity ... #Gauchers #Disease ... #Diagnosis #Signs
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... /symptoms of active ... decreased reflexes Pathophysiology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Chronic kidney disease ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... Presentation: - Disease ... course of the disease ... diagnosis column Treatment
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
variability in disease ... mood - Primary treatment ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... => Over time, active ... Months later, active ... FrozenShoulder #pathophysiology ... diagnosis #symptoms #signs
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pyrophosphatase activity ... Pseudogout #CPPD #Disease ... #Signs #Symptoms ... #Pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis: HLH signs ... absent NK cell activity ... • Bicytopenia Treatment ... diagnosis #management #treatment