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diagnosis hepatology differential management injury lfts transaminitis algorithm causes gastroenterology rheumatology elevated function hepatitis interpretation laboratory lupus medications pathophysiology tests
Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Pathophysiology Indirect Idiosyncratic ... BrighamChiefs #DILI ... #DrugInduced #Liver
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Management of Idiosyncratic ... Drug-induced Liver ... or symptoms of liver ... Drug #induced #Liver ... #Injury #Idiosyncratic
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... #Differential #DrugInduced ... Pharmacology #Causes #DILI
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 Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Diagnosis Algorithm DILI ... injury, Previous DILI ... hepatitis #DILI ... #DrugInduced #Liver
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... (>1000): • DILI ... (Drug-induced liver ... Hepatopathy (shock liver ... LouLectures #Liver
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Causes of Acute Liver ... • Iatrogenic: DILI ... Unconjugated Bili ... > 90% of Total Bili
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... of underlying liver ... disease, liver ... support, or liver ... Injury (DILI)
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... GTT, indirect bili ... MELD - Chronic liver ... disease work up - Liver ... US - Prior liver
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Trauma: Shock liver ... • Iatrogenic: DILI
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... abnormality vs bone Bili ... SinaiBmoreIMRes #Liver
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