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diagnosis differential management types cardiology algorithm clinical gastroenterology causes table pharmacology hematology nephrology rheumatology treatment comparison grading pulmonary classes pediatrics
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Transferrin • Gamma: IgM ... , IgG, IgA, RF, ... Subtypes #algorithm #classification
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome: - Acute poststreptococcal glomerulonephritis - Rapidly progressive
Berger disease (IgA ... Nephrotic #Syndromes #Classification
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
glomeruli • Ex: IgA ... Glomerulonephritis #RPGN #Classification
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia Classification ... 1: Monoclonal IgM ... (rarely IgG/lgA ... 2: Monoclonal IgM ... Cryoglobulinemia #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulins are Igs ... or polyclonal IgM ... • IgA vasculitis ... diagnosis #types #classification
Management of adult IgA Vasculitis (Henoch-Schönlein purpura) - Treatment algorithm for the management of IgAV patients
Management of adult IgA ... management of IgAV ... Management of IgA ... TerrierBen #IgA ... #Vasculitis #IGAV
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 1) Suggestive clinical manifestations
Diagnosis of IgA ... Elevated serum IgA ... vasculitis with IgA1 ... - Dominant IgA ... with vascular IgA
Commonly Used Diagnostic Tests for Celiac Disease Tissue transglutaminase (tTG) IgA antibodies - Most reliable noninvasive test
transglutaminase (tTG) IgA ... negative with IgA ... patients with IgA ... and specificity IgA ... disease less than IgA
Celiac Disease Testing Algorithm INDICATIONS FOR TESTING: Nonspecific symptoms (iron-deficiency anemia, failure to thrive, fever, skin
Immunoglobulin A • tTG IgA ... • tTG IgG and ... DGP IgGa • EMA ... IgG by IFA • DGP ... IgA • HLA testing
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... immune response, IgA ... (GD-IgA1). ... -> Decr IgA serum ... -> adhesion of IgA
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