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diagnosis differential management nephrology neurology hematology dermatology pediatrics peds cardiology endocrinology workup obgyn treatment acute ddxof hepatology types classes disorders
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Transferrin • Gamma: IgM ... , IgG, IgA, RF, ... Proteins #Subtypes #algorithm ... #classification
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia Classification ... (rarely IgG/lgA ... and polyclonal IgG ... and polyclonal IgG ... Cryoglobulinemia #Classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
allergies Type II - IgG ... antigen - IgG ... IgG can also mediate ... Type Ill - IgG and ... Hypersensitivity #Types #Classification
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
Anaphylaxis) Type II - IgG ... or IgM Cytotoxic ... reactions #Types #Classification
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... , Quantitative IgA ... , IgG, IgM (CVID ... patients if the cause ... Differential #Diagnosis #Causes
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm • GI disorders: Celiac disease, Crohn's disease,
Causes of Secondary ... IgA Nephropathy ... Differential Diagnosis Algorithm ... #Nephropathy #Causes ... Differential #Diagnosis #Algorithm
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup Algorithm ... maternal chromosomal causes ... 1 Antibodies, IgG ... Prothrombin Antibody, IgGa ... Hypercoagulable #Workup #Algorithm
Uveitis - Definition, Causes and SUN Classification Inflammation of the iris, ciliary body, vitreous, retina and/or choroid Incidence
and SUN Classification ... inhabitants 3rd leading cause ... retinal ischemia Causes ... Bartonella SUN Classification ... #SUN #Classification
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... and Extrinsic Causes ... autoimmune (most of the causes ... #Hemolysis #Classification ... #Algorithm
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Mediator: IgM ... + IgG • Immunological ... Immunological Mediator: IgG ... Reactions #Types #Classification
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