40 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... #Differential #
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
(HIT) • Suspected ... HIT Algorithm ... • "4 T's" clinical ... other sequelae of HIT ... #HIT #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Risks factor for HIV ... peripheral blood smear, HIV ... (CVID, WAS), (neurologic ... changes), high MCV anemia
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... etc) - Viral: HIV ... Antibody-mediated: ITP, HITT ... #Differential #
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
with suspected HIT ... the results of HIT ... probability of HIT ... #HIT #Heparin # ... Induced #Thrombocytopenia
Cotton Wool Spots

Caused by microinfarcts. Exploded ganglion cell axons extrude their axoplasm into retina. Long DDx:
hypertension, diabetes, HIV ... , severe anemia ... or thrombocytopenia ... ophthalmology #Clinical
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
(HIT) - Diagnosis ... likelihood of HIT ... in 30d) • H/o HIT ... management of HIT ... #HIT #Heparin
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... necrosis) • VIT ... Ig A vasculitis/HSP ... #nonpalpable #dermatology
Great Mimickers - SHALLOTS Mnemonic

S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
H _ HIV - Hepatitis ... dermatitis, dementia, anemia ... , thrombocytopenia ... sarcoma What doesn't HIV ... Mnemonic #Diagnosis #Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... infections/fevers • Thrombocytopenia ... - HCV - HIV ... immunodeficiency virus (HIV ... #oncology #hematology