21 results
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Approach to suspected Heparin-Induced ... Thrombocytopenia ... • "4 T's" clinical ... NephPrasad #Heparin ... #HIT #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... Megakaryopoiesis • Aplastic Anemia ... Quinidine • HIT ... #Differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia ... Diagnosis: • Clinical ... A/C if clinical ... #HIT #Heparin ... Management #Treatment #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Schistocytes, thrombocytopenia ... Diagnosis #Algorithm #workup ... #hematology #testing
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... Estimates of the clinical ... Diagnosis #Management #Hematology ... #HIT #Heparin # ... Induced #Thrombocytopenia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... deficiency) • HIT ... : Heparin-PF4 antibodies ... 100mg/dL) - Heparin ... treatment #management #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... - Hemolytic anemia ... Ig A vasculitis/HSP ... #nonpalpable #dermatology
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
for Causes of Thrombocytopenia ... A - Aplastic Anemia ... Toxin (Drug or Heparin-induced ... #Differential # ... Diagnosis #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... infections/fevers • Thrombocytopenia ... - HCV - HIV ... immunodeficiency virus (HIV ... #oncology #hematology