22 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... With associated pulmonary ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... Rheumatology ... involvement Sepsis - Immuno-compromise ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
that disrupts immune ... Others: Cellular immune ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... impaired cellular immune ... presentations: • Pulmonary ... vori Infectious Diseases ... #fungal #infectiousdiseases
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... antibiotics once stable ... shows a small, stable ... Lung #Abscess #pulmonary ... #differential #causes
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... normal in mild cases ... Avoid meds that ... #hematology
Differential diagnosis
The table summarizes the most common diseases, that present with consolidation.
Chronic diseases are indicated in
The table summarizes ... lobar pneumonia caused ... respond to the treatment ... #Pulmonary #CXR ... #Differential #Table
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... tract, and often causes ... #Differential #Diagnosis ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Necrotizing, pauci-immune ... respiratory tracts Immune ... tract, and often causes ... #rheumatology #
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... , and CXR with pulmonary ... #diagnosis #comparison ... #table