203 results
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
invasion, evasion of immune ... #Pathophysiology ... #Oncology #Melanoma
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
produced from normal immune ... a maladaptive immune ... self-antigens are the cause ... antigens are the cause ... Allergy #Immunology #pathophysiology
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... and Causes - ... #Jaundice #Pathophysiology ... #Unconjugated #Causes ... #Diagnosis
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... - Differential Diagnosis ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #Oncology
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Definition • Pathophysiology ... Aplastic #Anemia #diagnosis ... #oncology #hematololgy
Congestive Heart Failure - Causes, Pathophysiology and Differential Diagnosis
 • Dilated Cardiomyopathy 
 • Hypertrophic Cardiomyopathy
Heart Failure - Causes ... , Pathophysiology ... and Differential Diagnosis ... #Pathophysiology ... #Differential #Diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune ... Goodpasture's) Pauci-immune ... #differential #diagnosis
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... disease Rare causes ... malignancy - Immune ... #Differential #Diagnosis ... #Causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... - Differential Diagnosis ... legionella) • Immune ... #Differential #Diagnosis ... #Algorithm #Causes
The Pathophysiology of Fat Absorption and Causes of Malabsorption (steatorrhoea)

#Fat #Malabsorption #Pathophysiology #Differential #Steatorrhea #Diarrhea #Diagnosis
The Pathophysiology ... Absorption and Causes ... Malabsorption #Pathophysiology ... Steatorrhea #Diarrhea #Diagnosis