1578 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... mutations) • Immune ... Constitutional Syndromes ... HCV - HIV • Immune ... Aplastic #Anemia #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... (CML) • Felty Syndrome ... Significance (IDUS) • Immune ... diagnosis #hematology #oncology
Summary Table of Paraneoplastic Syndromes

#Diagnosis #Oncology #Paraneoplastic #Syndromes #Table
Paraneoplastic Syndromes ... #Diagnosis #Oncology ... Paraneoplastic #Syndromes
Paraneoplastic Syndromes

#Diagnosis #Oncology #Paraneoplastic #Syndromes #RebelEM
Paraneoplastic Syndromes ... #Diagnosis #Oncology ... Paraneoplastic #Syndromes
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... HEMATOLOGIC ONCOLOGIC ... Hyperviscosity Syndrome ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... Immune-mediated ... causes: • Susac syndrome ... disease • Cogan syndrome ... • Sjögren syndrome
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Pulmonary Renal Syndromes ... : • Pauci-Immune ... Cryoglobulinemia) • Immune ... Infection, Alport Syndrome
Check point inhibitors and Side Effects - Immune-related adverse events (IRAEs)

What are the side effects?
 -
Side Effects - Immune-related ... - Immune-related ... - Most immune-related ... AdverseEffects #Oncology
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
invasion, evasion of immune ... Pathophysiology #Oncology