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Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... consumption - Immune ... - ITP (immune ... - Non-immune ... Purpura #Bruising #Causes
Causes of Purpura - Differential Diagnosis Non-PalpabIe → Palpable • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... → Palpable • Thrombocytopenia ... Vasculitis (LCV), Immune ... nonpalpable #palpable #Causes
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
Vaccine-induced immune ... thrombotic thrombocytopenia ... The exact cause ... antibodies which cause ... Vaccine #Induced #immune
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... Hemolysis: • Immune-mediated ... Extravascular #Causes
Management of Immune Thrombocytopenia (ITP) . #Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
Management of Immune ... Thrombocytopenia ... #Idiopathic #Thrombocytopenic ... #Purpura #Immune ... #Thrombocytopenia
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
cell-mediated immune ... Weight Loss • Can cause ... , Neutropenia, Thrombocytopenia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... infections/fevers • Thrombocytopenia ... and petechiae Causes ... HCV - HIV • Immune
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Reactions Immune ... ): Most common immune ... Causes purpura & ... severe thrombocytopenia ... Non-Immune Mediated
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
(specifically immune ... thrombocytopenia ... DDX - Other causes
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Reactions: • Immune ... ): Most common immune ... Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause
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