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diagnosis differential hematology causes endocrinology insufficiency pancytopenia dermatology eosinophil eosinophilia evaluation gout hemolytic hyperuricemia hypokalemia laboratory mds myelodysplasia myelodysplastic naildisorders
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm Primary Adrenal Insufficiency: • Autoimmune primary adrenal insufficiency • Adrenoleukodystrophy,
Differential Diagnosis Workup ... Algorithm Primary ... Adrenoleukodystrophy, genetic disorder ... or tuberculosis Secondary ... #Algorithm #endocrinology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... 1,500 cells/µL Workup ... • Screen for secondary
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Consumption Disorders ... Eating disorders ... Acquired Aplastic Anemia
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Consumption Disorders ... Eating disorders ... Acquired Aplastic Anemia
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Differential Diagnosis Algorithm ... • Starvation Secondary ... Lymphoproliferative Disorders ... - Hemolytic Anemia ... High purine diet Secondary
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... discoloration) • Chronic renal ... NailDisorders #Systemic #Secondary ... Differential #Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Consider RBC membrane disorder ... #workup #hematology ... #testing
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
antibody test Secondary ... origin of the disorder ... a hypothalamic disorder ... laboratory #diagnosis #testing ... endocrinology #workup
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
hypomagnesemia), Eating ... disorders GI Losses ... Villous adenoma Renal ... hyperaldosteronism, Secondary ... megaloblastic anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... DDX: Rule Out Secondary ... Neutropenia • Platelet Disorders ... Workup: • Complete
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