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management rheumatology differential neurology dermatology hematology sle types back birth bracing bruising cerebral children curvature defects druginduced dystrophy erythematosus fusion
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... permeability Diagnosis ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... #rheumatology #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... of SLE versus DIL ... Positive in 60-80% of cases ... life-threatening • Treatment ... Erythematosus #Diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor and lupus ... Willebrand syndrome • Lupus ... discern these causes ... #Differential #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... Extravascular #Causes
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
and treatment can ... Inflammatory causes ... syndrome • Systemic lupus ... optica spectrum disorder ... #differential #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... (e.g. systemic lupus ... Cryoglobulins #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Differential Diagnosis ... Vasculitis - Collagen disorders ... fulminans - DIC ... Autoimmune Vasculitis (lupus
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... Differential DX ... myasthenia Diagnosis ... Clinical DX: - ... Myasthenia #Gravis #diagnosis
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... autism spectrum disorder ... , or any other cause ... vasculitis Treatment ... Pathophysiology #Nutrition #Diagnosis
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