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diagnosis differential mgus chronic cll gammopathy leukemia lymphocytic significance workup agglutinin anemia bleeding cell clinical cold disease gammopathies gap globulin
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology ... #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma and Monoclonal ... if this is is monoclonal ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... disorder characterized ... , or a related disorder ... #Significance #hematology ... #diagnosis #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... infection, autoimmune disorder ... IgM Includes Disorders ... hemolytic #anemia #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Rare Disorder: ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... are a group of disorders ... Neutropenia • Platelet Disorders ... #diagnosis #hematology ... #oncology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Evaluating Bleeding Disorders ... Marfan syndrome, ... osteogenesis imperfecta ... #Bleeding #Disorders ... pediatrics #diagnosis #hematology
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