17 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Relevant HES Variants ... disorders • Diagnosis ... #Syndrome #HES ... #Hematology #eosinophilia ... eosinophils #diagnosis #management
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia ... Syndrome (HES) ... eosinophilia Secondary Causes ... #Syndrome #HES ... eosinophilia #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disease - DIC/TTP/HUS ... Kasabach-Merritt syndrome ... : • DIC, TTP/HUS ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... • Has a UGT1A1 ... and stress may cause ... Congenital #bilirubin #hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... (HUS) • Other ... lymphoproliferative disorders ... differential #diagnosis #hematology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Ketosis Disorders ... of re-feeding syndrome ... ketoacidosis (DKA) - caused ... Glucosuria causes ... differential #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... cerebritis #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... a gas exchange disorder ... lung disease Caused ... hepatopulmonary #syndrome ... #treatment #hepatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... Rule out other causes ... diagnosis #management ... #Dermatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology