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management hematology differential treatment lupus neurology oncology signs sle symptoms syndrome classification erythematosus hemophagocytic hlh lymphohistiocytosis psychiatry summary systemic adhd
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... PT, aPTT(liver disease ... #Causes #Workup ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... , PRES Pathophysiology ... autoantibodies that will cause ... CNS #neurology #rheumatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... 109 mm Hg) with clinical ... Renal parenchymal disease ... Neurologic disorders
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Evolution: Chronic disease ... Management #Summary #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... • Autoimmune diseases ... classification #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... treatment #summary #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulinemia Associated Disorders ... Cryofibrinogenemia Clinical ... : • + Clinical ... cryoglobulins • Negative causes ... #rheumatology #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... late adulthood • Diagnosis ... to 8 years Clinical ... conditions Diagnosis ... DDX - Other causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... super-antigen mediated disease ... Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... MCTD - Bechet disease
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