10 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... underlying hematologic disorders ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... than 1500 and clinical ... - Immunologic disorders ... #diagnosis #hematology ... #differential #
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Diagnosis and Causes Clinical ... Fibrosis, Hyper-eosinophilc ... Syndrome, Endocardial ... Sarcomeric Protein Disorders ... #cardiology #algorithm
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Clinical Features ... Erythematosus #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... SLE), Sjogren's Syndrome ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology ... #diagnosis #differential
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
Hypertensive Disorders ... patients • HELLP: Syndrome ... diagnosis so have high clinical ... htn #obstetrics #cardiology ... #differential #
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... ESRD & CAD • Eosinophilic ... GI Disorders ... cell activation syndrome ... #Diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... Evaluating Bleeding Disorders ... Marfan syndrome, ... osteogenesis imperfecta ... pediatrics #diagnosis #hematology
Night Sweats - Differential Diagnosis Framework

Night sweats are a nonspecific symptom that patients commonly experience and
Night Sweats - Differential ... serious underlying disorder ... alcohol, heroin RHEUMATOLOGIC ... Chronic fatigue syndrome ... disease • Chronic eosinophilic